Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18736058 | 0.88 | MTNR1A (0.72) | NPC1PKMRAB9APOLBKMT2A | |
| SCHEMBL6376395 | 0.87 | MTNR1A (0.71) | POLBKMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL14027267 | 0.86 | ALDH1A1 (0.72) | POLBKMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL14027269 | 0.86 | ALDH1A1 (0.72) | POLBKMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL5211526 | 0.85 | MTNR1A (0.82) | POLBKMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL6376361 | 0.84 | ALDH1A1 (0.73) | POLBKMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL6377560 | 0.84 | ALDH1A1 (0.73) | POLBKMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL29066085 | 0.84 | MTNR1A (0.62) | NPC1PKMRAB9AKMT2AMEN1 | |
| SCHEMBL1114985 | 0.84 | NPC1 (0.63) | NPC1PKMRAB9AKMT2AMEN1 | |
| SCHEMBL31011346 | 0.84 | NPC1 (0.63) | NPC1PKMRAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |