Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4526740 | 1.00 | MAPT (0.35) | MAPTCYP3A4TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL4526732 | 0.91 | MAPT (0.35) | MAPTCYP3A4TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL9416811 | 0.91 | MAPT (0.35) | MAPTCYP3A4TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL14035534 | 0.90 | MAPT (0.34) | MAPTHTTCYP4F2CYP4A11 | |
| SCHEMBL4507473 | 0.85 | GRM2 (0.33) | — | |
| SCHEMBL4507468 | 0.85 | GRM2 (0.33) | — | |
| SCHEMBL8623466 | 0.81 | MAPT (0.43) | MAPTCYP4F2CYP4A11 | |
| SCHEMBL30707215 | 0.75 | MAPT (0.36) | MAPTNPSR1CYP4F2CYP4A11 | |
| SCHEMBL15483730 | 0.74 | CYP3A4 (0.34) | MAPTCYP3A4TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL13757812 | 0.73 | GRM2 (0.36) | MAPTCYP3A4TSHRMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |