Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416811 | 1.00 | MAPT (0.35) | MAPTCYP3A4TSHRCYP4F2CYP4A11 | |
| SCHEMBL9416740 | 0.91 | MAPT (0.35) | MAPTCYP3A4TSHRCYP4F2CYP4A11 | |
| SCHEMBL4526740 | 0.91 | MAPT (0.35) | MAPTCYP3A4TSHRCYP4F2CYP4A11 | |
| SCHEMBL30707215 | 0.83 | MAPT (0.36) | MAPTCYP4F2CYP4A11NPSR1L3MBTL1 | |
| SCHEMBL11783192 | 0.81 | PTPN1 (0.35) | MAPTCYP4F2CYP4A11NPSR1ALDH1A1 | |
| SCHEMBL14035534 | 0.80 | MAPT (0.34) | MAPTCYP4F2CYP4A11HTTALDH1A1 | |
| SCHEMBL15483730 | 0.78 | CYP3A4 (0.34) | MAPTCYP3A4TSHRNPSR1LMNA | |
| SCHEMBL13757812 | 0.77 | GRM2 (0.36) | MAPTCYP3A4TSHRNPSR1LMNA | |
| SCHEMBL3369422 | 0.77 | GRM2 (0.36) | MAPTCYP3A4TSHRNPSR1LMNA | |
| SCHEMBL4507473 | 0.77 | GRM2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993998-B1 | 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES | UCB PHARMA SA (BE) | 2013-08-21 | — | — | EP | disclosed |
| EP-1993998-B1 | 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES | UCB PHARMA SA (BE) | 2013-08-21 | — | — | EP | disclosed |
| US-8076493-B2 | 3-carboxy-2-oxo-1-pyrrolidine derivatives and their uses | UCB PHARMA, S.A. (BE) | 2011-12-13 | — | — | US | disclosed |
| US-8076493-B2 | 3-carboxy-2-oxo-1-pyrrolidine derivatives and their uses | UCB PHARMA, S.A. (BE) | 2011-12-13 | — | — | US | disclosed |
| US-8076493-B2 | 3-carboxy-2-oxo-1-pyrrolidine derivatives and their uses | UCB PHARMA, S.A. (BE) | 2011-12-13 | — | — | US | disclosed |
| US-20090012313-A1 | 3-Carboxy-2-Oxo-1-Pyrrolidine Derivatives and Their Uses | UCB PHARMA, S.A. (BE) | 2009-01-08 | — | — | US | disclosed |
| US-20090012313-A1 | 3-Carboxy-2-Oxo-1-Pyrrolidine Derivatives and Their Uses | UCB PHARMA, S.A. (BE) | 2009-01-08 | — | — | US | disclosed |
| US-20090012313-A1 | 3-Carboxy-2-Oxo-1-Pyrrolidine Derivatives and Their Uses | UCB PHARMA, S.A. (BE) | 2009-01-08 | — | — | US | disclosed |
| EP-1993998-A1 | 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES | UCB Pharma, S.A. (BE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007065634-A1 | 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES | UCB PHARMA, S.A. (BE) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012313-A1 | 3-Carboxy-2-Oxo-1-Pyrrolidine Derivatives and Their Uses | ALDH18A1, PYCR1, OPRD1 | MAPT 3528/4885CYP3A4 24/4885TSHR 4398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.