Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DNTT | P04053 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4526740 | 0.90 | MAPT (0.35) | MAPTCYP4F2CYP4A11HTT | |
| SCHEMBL9416740 | 0.90 | MAPT (0.35) | MAPTCYP4F2CYP4A11HTT | |
| SCHEMBL4526732 | 0.80 | MAPT (0.35) | MAPTCYP4F2CYP4A11HTTALDH1A1 | |
| SCHEMBL9416811 | 0.80 | MAPT (0.35) | MAPTCYP4F2CYP4A11HTTALDH1A1 | |
| SCHEMBL8623466 | 0.79 | MAPT (0.43) | MAPTCYP4F2CYP4A11 | |
| SCHEMBL28747535 | 0.75 | ARG1 (0.35) | ALDH1A1EPHX2DNTTCPB2 | |
| SCHEMBL29681754 | 0.75 | ARG1 (0.35) | ALDH1A1EPHX2DNTTCPB2 | |
| SCHEMBL4507473 | 0.74 | GRM2 (0.33) | — | |
| SCHEMBL4507468 | 0.74 | GRM2 (0.33) | — | |
| SCHEMBL4868042 | 0.73 | MAPT (0.36) | MAPTHTTALDH1A1EPHX2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505945-B1 | SUBSTITUTED CYCLOALKYL P1' HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-11-05 | — | — | EP | disclosed |