Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416859 | 0.86 | KMT2A (0.47) | CYP3A4TSHRALDH1A1CNR2CNR1 | |
| SCHEMBL2595399 | 0.86 | TSHR (0.62) | CYP3A4TSHRALDH1A1GLATP53 | |
| SCHEMBL374161 | 0.85 | ALDH1A1 (0.45) | TSHRALDH1A1GLASLC6A2SLC6A4 | |
| SCHEMBL9416869 | 0.80 | MAPT (0.40) | CYP3A4ALDH1A1GPBAR1MAPTLMNA | |
| SCHEMBL3646180 | 0.77 | CYP3A4 (0.65) | CYP3A4TSHRALDH1A1GLACNR2 | |
| SCHEMBL11738442 | 0.73 | CYP3A4 (0.60) | CYP3A4TSHRALDH1A1GLACNR2 | |
| SCHEMBL27508524 | 0.72 | CYP3A4 (0.58) | CYP3A4TSHRALDH1A1GLACNR2 | |
| SCHEMBL6195877 | 0.72 | CYP3A4 (0.58) | CYP3A4TSHRALDH1A1GLACNR2 | |
| SCHEMBL1114850 | 0.71 | CYP3A4 (0.54) | CYP3A4TSHRALDH1A1GLACNR2 | |
| SCHEMBL1114715 | 0.70 | CYP3A4 (0.53) | CYP3A4TSHRALDH1A1GLACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |