Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416888 | 0.85 | EGFR (0.47) | MAPK14KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL8765373 | 0.85 | CNR1 (0.48) | MAPK14KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL9416817 | 0.82 | CNR1 (0.46) | MAPK14KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL9416864 | 0.82 | CNR1 (0.52) | MAPK14KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL9416828 | 0.81 | EGFR (0.44) | MAPK14KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL26789821 | 0.81 | EGFR (0.55) | MAPK14KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL2951112 | 0.81 | RAB9A (0.77) | MAPK14KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL1459685 | 0.79 | MEN1 (0.53) | MAPK14KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL4895893 | 0.79 | NPC1 (0.61) | KMT2ARAB9AMEN1NPC1FLT3 | |
| SCHEMBL5252328 | 0.78 | KMT2A (0.71) | MAPK14KMT2ARAB9AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220947-B1 | Polyfluoroalkylisoxazolylamines, their preparation and use | SHIONOGI & CO (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-4797492-A | INTERMEDIATES FOR BACTERICIDES; HERBICIDES OR FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1989-01-10 | — | — | US | disclosed |
| EP-0220947-A2 | Polyfluoroalkylisoxazolylamines, their preparation and use | SHIONOGI & CO., LTD. (JP) | 1987-05-06 | — | — | EP | disclosed |