Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.45 |
| ▸ | CNR2 | P34972 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416804 | 0.85 | MAPK14 (0.55) | EGFRMAPK14CNR1CNR2NPC1 | |
| SCHEMBL28467424 | 0.85 | EGFR (0.48) | EGFRMAPK14CNR1CNR2SMN1; SMN2 | |
| SCHEMBL4112548 | 0.84 | EGFR (0.66) | EGFRMAPK14SMN1; SMN2TDP1NPC1 | |
| SCHEMBL9416864 | 0.83 | CNR1 (0.52) | EGFRMAPK14CNR1CNR2SMN1; SMN2 | |
| SCHEMBL8765373 | 0.82 | CNR1 (0.48) | EGFRMAPK14CNR1CNR2SMN1; SMN2 | |
| SCHEMBL9416828 | 0.81 | EGFR (0.44) | EGFRMAPK14CNR1CNR2SMN1; SMN2 | |
| SCHEMBL26789821 | 0.81 | EGFR (0.55) | EGFRMAPK14CNR1CNR2SMN1; SMN2 | |
| SCHEMBL9416817 | 0.79 | CNR1 (0.46) | EGFRMAPK14CNR1CNR2SMN1; SMN2 | |
| SCHEMBL9893035 | 0.78 | EGFR (0.51) | EGFRMAPK14SMN1; SMN2TDP1NPC1 | |
| SCHEMBL4895893 | 0.76 | NPC1 (0.61) | HDAC4CNR1CNR2SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220947-B1 | Polyfluoroalkylisoxazolylamines, their preparation and use | SHIONOGI & CO (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-4797492-A | INTERMEDIATES FOR BACTERICIDES; HERBICIDES OR FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1989-01-10 | — | — | US | disclosed |
| EP-0220947-A2 | Polyfluoroalkylisoxazolylamines, their preparation and use | SHIONOGI & CO., LTD. (JP) | 1987-05-06 | — | — | EP | disclosed |