Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Xylene SCHEMBL9416837 | 0.91 | F2 (0.43) | LMNAMEN1KMT2AF2PRSS1 | |
| Biphenyl SCHEMBL9416862 | 0.86 | MEN1 (0.40) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9844187 | 0.79 | TSHR (0.33) | LMNATSHRCA1CA2CA9 | |
| Toluene SCHEMBL27505113 | 0.76 | LMNA (0.42) | LMNATSHRALOX12ACHEMEN1 | |
| Toluene SCHEMBL28102361 | 0.74 | TSHR (0.61) | LMNATSHRALOX12ACHEMEN1 | |
| Toluene SCHEMBL2490584 | 0.74 | TSHR (0.61) | LMNATSHRALOX12ACHEMEN1 | |
| Toluene SCHEMBL30489134 | 0.74 | TSHR (0.61) | LMNATSHRALOX12ACHEMEN1 | |
| Toluene SCHEMBL7587487 | 0.74 | LMNA (0.44) | LMNATSHRALOX12ACHEMEN1 | |
| Toluene SCHEMBL27846814 | 0.73 | LMNA (0.53) | LMNATSHRALOX12ACHEMEN1 | |
| Toluene SCHEMBL10321989 | 0.73 | LMNA (0.53) | LMNATSHRALOX12ACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407886-B1 | Method for producing plastic hollow parts with foamed walls | HOECHST AG (DE) | 1994-02-23 | — | — | EP | disclosed |
| EP-0407886-A2 | Method for producing plastic hollow parts with foamed walls | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-16 | — | — | EP | disclosed |