Toluene

Toluene

SCHEMBL7587487

Cc1ccccc1.NC(=O)NNS(=O)(=O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.44
KAT6A Q92794 3/20 0.41
POLB P06746 2/20 0.40
BCAT1 P54687 1/20 0.40
ALOX12 P18054 2/20 0.39
TSHR P16473 1/20 0.39
ACHE P22303 1/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
GAA P10253 2/20 0.38
HPGD P15428 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
CYP2D6 P10635 2/20 0.38
PTGS2 P35354 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL9416754 0.84 MEN1 (0.35) LMNAKAT6ABCAT1TSHRKMT2A
Styrene SCHEMBL28429639 0.78 ALDH1A1 (0.45) KAT6ABCAT1TSHRKMT2AMEN1
SCHEMBL2236617 0.78
Toluene SCHEMBL761209 0.77 LMNA (0.50) LMNAALOX12TSHRACHEKMT2A
Toluene SCHEMBL9416863 0.77 LMNA (0.50) LMNAALOX12TSHRACHEKMT2A
Toluene SCHEMBL30489134 0.76 TSHR (0.61) LMNAALOX12TSHRACHEKMT2A
Toluene SCHEMBL28102361 0.76 TSHR (0.61) LMNAALOX12TSHRACHEKMT2A
Methane SCHEMBL9416768 0.76 TSHR (0.33) LMNATSHRTDP1KDM4ECYP1A2
Toluene SCHEMBL2490584 0.76 TSHR (0.61) LMNAALOX12TSHRACHEKMT2A
Toluene SCHEMBL10321989 0.74 LMNA (0.53) LMNAPOLBALOX12TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103087663-A Reinforcing film matrix composition and its preparation method, reinforcing film and steel plate composite material BYD CO LTD 2013-05-08 CN claimed
CN-1321150-C Thermoplastic expanded NVH material and its production method SAIC MOTOR CO LTD (CN) 2007-06-13 CN claimed
CN-1730536-A Thermoplastic expanded NVH material and its production method SAIC MOTOR CORP LTD (CN) 2006-02-08 CN claimed
EP-0948428-B1 METHOD FOR MANUFACTURING A MONOLITHIC PLASTIC OBJECT, AND AN OBJECT OBTAINED WITH THIS METHOD CORELL RESIN TECHNOLOGY BV (NL) 2002-10-09 EP claimed
US-6277896-B1 Method for manufacturing a monolithic plastic object, and an object obtained with this method CORELL RESIN TECHNOLOGY B.V. (NL) 2001-08-21 US claimed
CN-107805385-B Spraying-free nylon material and preparation method thereof 江苏博云塑业股份有限公司 2020-12-15 CN disclosed
CN-108676352-A A kind of printed circuit board drilling backing plate and preparation method thereof 深圳市柳鑫实业股份有限公司 2018-10-19 CN disclosed
CN-103087663-A Reinforcing film matrix composition and its preparation method, reinforcing film and steel plate composite material BYD CO LTD 2013-05-08 CN disclosed
CN-1321150-C Thermoplastic expanded NVH material and its production method SAIC MOTOR CO LTD (CN) 2007-06-13 CN disclosed
CN-1730536-A Thermoplastic expanded NVH material and its production method SAIC MOTOR CORP LTD (CN) 2006-02-08 CN disclosed