Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13725441 | 0.86 | HTT (0.59) | CETPHTTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9336275 | 0.86 | HTT (0.59) | CETPHTTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8197973 | 0.85 | HTT (0.58) | HTTL3MBTL1LMNASMN1; SMN2MAPT | |
| SCHEMBL24486768 | 0.85 | HTT (0.63) | HTTL3MBTL1LMNASMN1; SMN2MAPT | |
| SCHEMBL1667805 | 0.83 | HTT (0.72) | HTTL3MBTL1LMNASMN1; SMN2MAPT | |
| SCHEMBL1442202 | 0.83 | LMNA (0.56) | CETPHTTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8190950 | 0.82 | HTT (0.56) | HTTL3MBTL1LMNASMN1; SMN2MAPT | |
| SCHEMBL9336327 | 0.82 | CETP (0.60) | CETPHTTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8290406 | 0.82 | HTT (0.70) | HTTL3MBTL1LMNASMN1; SMN2MAPT | |
| Ammonia Solution, Strong SCHEMBL10743947 | 0.82 | HTT (0.70) | HTTL3MBTL1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300679-A | Antagonists to 4-aminobutyric acid | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |