Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021886 | 0.89 | RAB9A (0.39) | LMNACYP2C9MAPTALDH1A1RAB9A | |
| SCHEMBL11423075 | 0.88 | LMNA (0.55) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL11403789 | 0.88 | LMNA (0.55) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL11405979 | 0.88 | LMNA (0.55) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9711900 | 0.87 | CYP2C9 (0.45) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9711909 | 0.87 | CYP2C9 (0.45) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL12768626 | 0.87 | LMNA (0.57) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL11411848 | 0.87 | LMNA (0.48) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9189118 | 0.87 | LMNA (0.57) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL12768386 | 0.87 | LMNA (0.57) | LMNANPC1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267585-B1 | FLUOROALKANE DERIVATIVE, ITS COMPOSITION AND LIQUID CRYSTAL DEVICE USING SAME | CANON KABUSHIKI KAISHA (JP) | 1993-09-15 | — | — | EP | claimed |
| EP-0267585-A2 | Fluoroalkane derivative, its composition and liquid crystal device using same | CANON KABUSHIKI KAISHA (JP) | 1988-05-18 | — | — | EP | claimed |
| US-5328639-A | Ether esters or thioesters | CANON KABUSHIKI KAISHA (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0267585-B1 | FLUOROALKANE DERIVATIVE, ITS COMPOSITION AND LIQUID CRYSTAL DEVICE USING SAME | CANON KABUSHIKI KAISHA (JP) | 1993-09-15 | — | — | EP | disclosed |
| EP-0267585-A2 | Fluoroalkane derivative, its composition and liquid crystal device using same | CANON KABUSHIKI KAISHA (JP) | 1988-05-18 | — | — | EP | disclosed |