Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.48 |
| ▸ | FDPS | P14324 | 6/20 | 0.48 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.45 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.45 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6432219 | 0.85 | FDPS (0.60) | METAP1FDPSLAP3 | |
| SCHEMBL3889795 | 0.84 | FDPS (0.62) | METAP1FDPSLAP3 | |
| SCHEMBL6123422 | 0.81 | FDPS (0.63) | FDPSLAP3 | |
| SCHEMBL27670718 | 0.80 | METAP1 (0.54) | METAP1FDPSGABBR2GABBR1LAP3 | |
| SCHEMBL3886749 | 0.80 | FDPS (0.65) | METAP1FDPSLAP3 | |
| SCHEMBL8825620 | 0.78 | FDPS (0.62) | METAP1FDPSLAP3 | |
| SCHEMBL5778166 | 0.78 | FDPS (0.67) | FDPSLAP3 | |
| Octadecylamine SCHEMBL27742453 | 0.77 | LAP3 (0.55) | FDPSLAP3 | |
| SCHEMBL11500908 | 0.76 | FDPS (0.68) | FDPSLAP3 | |
| SCHEMBL16799205 | 0.76 | FDPS (0.68) | FDPSLAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300679-A | Antagonists to 4-aminobutyric acid | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |