Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 11/20 | 0.53 |
| ▸ | PNP | P00491 | 3/20 | 0.34 |
| ▸ | POLG | P54098 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858364 | 0.94 | HPRT1 (0.51) | HPRT1PNPNOS1POLB | |
| SCHEMBL9683728 | 0.86 | HPRT1 (0.47) | HPRT1PNPNOS1 | |
| SCHEMBL9685499 | 0.85 | HPRT1 (0.47) | HPRT1PNPNOS1 | |
| SCHEMBL9417162 | 0.84 | HPRT1 (0.72) | HPRT1PNPPOLB | |
| SCHEMBL9857631 | 0.84 | HPRT1 (0.54) | HPRT1PNPPOLGNOS1POLB | |
| SCHEMBL9674751 | 0.83 | HPRT1 (0.44) | HPRT1PNPNOS1 | |
| SCHEMBL9417148 | 0.81 | HPRT1 (0.57) | HPRT1MEN1KMT2A | |
| SCHEMBL9857606 | 0.78 | HPRT1 (0.69) | HPRT1PNP | |
| SCHEMBL8742819 | 0.77 | HPRT1 (0.45) | HPRT1PNPNOS1 | |
| SCHEMBL9685196 | 0.77 | HPRT1 (0.46) | HPRT1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319228-B1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1994-11-02 | — | — | EP | claimed |
| US-5247085-A | Phosphonate containing purine compounds | BEECHAM GROUP P.L.C. (GB) | 1993-09-21 | — | — | US | claimed |
| EP-0319228-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1989-06-07 | — | — | EP | claimed |
| EP-0319228-B1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1994-11-02 | — | — | EP | disclosed |
| US-5247085-A | Phosphonate containing purine compounds | BEECHAM GROUP P.L.C. (GB) | 1993-09-21 | — | — | US | disclosed |
| EP-0319228-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1989-06-07 | — | — | EP | disclosed |