Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 10/20 | 0.47 |
| ▸ | PNP | P00491 | 9/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683728 | 0.97 | HPRT1 (0.47) | HPRT1PNPNOS1 | |
| SCHEMBL9858364 | 0.88 | HPRT1 (0.51) | HPRT1PNPNOS1 | |
| SCHEMBL9417138 | 0.85 | HPRT1 (0.53) | HPRT1PNPNOS1 | |
| SCHEMBL9683454 | 0.84 | HPRT1 (0.61) | HPRT1PNP | |
| SCHEMBL9674751 | 0.83 | HPRT1 (0.44) | HPRT1PNPNOS1 | |
| SCHEMBL9857631 | 0.82 | HPRT1 (0.54) | HPRT1PNPNOS1 | |
| SCHEMBL9684323 | 0.81 | HPRT1 (0.62) | HPRT1PNP | |
| SCHEMBL9685196 | 0.81 | HPRT1 (0.46) | HPRT1PNP | |
| SCHEMBL8742819 | 0.79 | HPRT1 (0.45) | HPRT1PNPNOS1 | |
| SCHEMBL4242270 | 0.78 | HPRT1 (0.50) | HPRT1PNPNOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | claimed |
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |