SCHEMBL9417246

SCHEMBL9417246

CC=C(O)C(=O)OCCCOc1cc(O)c(C(=O)c2ccccc2)cc1S

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.46
MAPT P10636 5/20 0.46
HPGD P15428 3/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP3A4 P08684 1/20 0.46
RECQL P46063 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ALDH1A1 P00352 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPK1 P28482 2/20 0.41
HTT P42858 2/20 0.41
CYP1A2 P05177 1/20 0.41
PGR P06401 1/20 0.41
CYP2D6 P10635 1/20 0.41
SLC6A2 P23975 1/20 0.41
PDE4A P27815 1/20 0.41
CYP2C19 P33261 1/20 0.41
HRH1 P35367 1/20 0.41
SLC6A3 Q01959 1/20 0.41
PDE4D Q08499 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL588978 0.82 HPGD (0.59) LMNAHPGDCYP3A4ALDH1A1KMT2A
SCHEMBL7600183 0.76 HPGD (0.49) LMNAMAPTHPGDKDM4ECYP3A4
SCHEMBL9654689 0.75 HPGD (0.43) LMNAMAPTHPGDKDM4ERECQL
SCHEMBL3794332 0.75 TSHR (0.51) LMNACYP3A4HSD17B10ALDH1A1KMT2A
SCHEMBL27890882 0.75 GAA (0.59) LMNAMAPTKDM4EALDH1A1MAPK1
SCHEMBL13382344 0.74 MAPT (0.75) LMNAMAPTHPGDKDM4ECYP3A4
SCHEMBL9417227 0.73 HPGD (0.54) LMNAMAPTHPGDCYP3A4ALDH1A1
SCHEMBL9417163 0.73 HPGD (0.54) LMNAHPGDCYP3A4ALDH1A1MAPK1
SCHEMBL9417244 0.72 LMNA (0.44) LMNAMAPTHPGDKDM4ECYP3A4
SCHEMBL10946685 0.71 TDP1 (0.50) MAPTRECQLALDH1A1HTTPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0475149-B1 Coating composition and resin article coated thereby NIPPON ARC CO LTD (JP) 1994-11-09 EP disclosed
US-5250359-A Weather resistant, abrasion resistant undercoatings NIPPON ARC CO., LTD. (JP) 1993-10-05 US disclosed
US-5191045-A Protective coatings with radiation resistance for moldings NIPPON ARC CO., LTD. (JP) 1993-03-02 US disclosed
EP-0475149-A2 Coating composition and resin article coated thereby NIPPON ARC CO., LTD. (JP) 1992-03-18 EP disclosed