SCHEMBL7600183

SCHEMBL7600183

CC=C(O)C(=O)OCCCc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.49
LMNA P02545 3/20 0.49
ALDH1A1 P00352 1/20 0.49
CYP1A2 P05177 1/20 0.49
PGR P06401 1/20 0.49
CYP2D6 P10635 1/20 0.49
SLC6A2 P23975 1/20 0.49
PDE4A P27815 1/20 0.49
MAPK1 P28482 1/20 0.49
CYP2C19 P33261 1/20 0.49
HRH1 P35367 1/20 0.49
HTT P42858 1/20 0.49
SLC6A3 Q01959 1/20 0.49
PDE4D Q08499 1/20 0.49
MEN1 O00255 1/20 0.45
USP2 O75604 1/20 0.45
GAA P10253 1/20 0.45
KMT2A Q03164 1/20 0.45
KEAP1 Q14145 1/20 0.45
NFE2L2 Q16236 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL588978 0.85 HPGD (0.59) HPGDLMNAALDH1A1CYP1A2PGR
SCHEMBL23196587 0.82 THRB (0.46) HPGDLMNAALDH1A1CYP1A2PGR
SCHEMBL1823463 0.79 HPGD (0.48) HPGDLMNAALDH1A1CYP1A2PGR
SCHEMBL29985941 0.79 HPGD (0.48) HPGDLMNAALDH1A1CYP1A2PGR
SCHEMBL28328951 0.79 PPARA (0.62) HPGDLMNAALDH1A1CYP1A2PGR
SCHEMBL29260298 0.77 LMNA (0.58) HPGDLMNAALDH1A1CYP1A2PGR
SCHEMBL9417246 0.76 LMNA (0.46) HPGDLMNAALDH1A1CYP1A2PGR
SCHEMBL8461758 0.76 PPARA (0.72) HPGDLMNAALDH1A1CYP1A2PGR
SCHEMBL4285667 0.76 PPARA (0.72) HPGDLMNAALDH1A1CYP1A2PGR
SCHEMBL31220575 0.76 PPARA (0.72) HPGDLMNAALDH1A1CYP1A2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5002979-A Hyydrogenorganosilicon monomer, organosilicon, fluoroorgano monomer, a hydrophobic monomer and a crosslinking agent BAUSCH & LOMB INCORPORATED (US) 1991-03-26 US claimed
EP-0211067-B1 OXYGEN-PERMEABLE LENSES Bausch & Lomb Incorporated (US) 1991-03-13 EP claimed
EP-0211067-A1 OXYGEN-PERMEABLE LENSES. BAUSCH & LOMB (US) 1987-02-25 EP claimed
EP-0209597-A1 EXTENDED-WEAR LENSES Bausch & Lomb Incorporated (US) 1987-01-28 EP claimed
WO-1986004342-A1 OXYGEN-PERMEABLE LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO claimed
WO-1986004343-A1 EXTENDED-WEAR LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO claimed
EP-1250392-A1 TRANSFER ADHESIVE TAPE Henkel Kommanditgesellschaft auf Aktien (DE) 2002-10-23 EP disclosed
WO-2001044397-A1 TRANSFER ADHESIVE TAPE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-06-21 WO disclosed
EP-0596418-B1 Releasable flexible fabric, process for its production and use ZWECKFORM BUERO PROD GMBH (DE) 1999-08-18 EP disclosed
EP-0577768-B1 PRESSURE-SENSITIVE ADHESIVE TAPE AND A PROCESS FOR PRODUCING SAME MINNESOTA MINING & MFG (US) 1997-05-21 EP disclosed
US-5518811-A HAVING BIAXIALLY ORIENTED BACKING WITH LAYER OF LOW ADHESION BACKSIZE ON SURFACE NOT BEARING PRESSURE SENSITIVE ADHESIVE AND COMMINGLED LAYER BETWEEN BACKING AND ADHESIVE FORMED DURING TRANSVERSE ORIENTATION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-21 US disclosed
EP-0632423-A2 Panel for repeatedly positioning, fixing and release of non-selfadhesive sheets ZWECKFORM Büro-Produkte GmbH (DE) 1995-01-04 EP disclosed
EP-0596418-A2 Releasable flexible fabric, process for its production and use ZWECKFORM Büro-Produkte GmbH (DE) 1994-05-11 EP disclosed
EP-0215817-A1 CONTINUOUS-WEAR LENSES. BAUSCH & LOMB (US) 1987-04-01 EP disclosed
EP-0211067-A1 OXYGEN-PERMEABLE LENSES. BAUSCH & LOMB (US) 1987-02-25 EP disclosed
EP-0209597-A1 EXTENDED-WEAR LENSES Bausch & Lomb Incorporated (US) 1987-01-28 EP disclosed
WO-1986004342-A1 OXYGEN-PERMEABLE LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO disclosed
WO-1986004341-A1 CONTINUOUS-WEAR LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO disclosed
WO-1986004343-A1 EXTENDED-WEAR LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO disclosed
US-4533595-A MULTILAYER: POLYCARBONATE BASE, SILICONE COATING, AND ADDITION POLYMER LAYER GENERAL ELECTRIC COMPANY (US) 1985-08-06 US disclosed