Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.56 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | TOP1 | P11387 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417240 | 0.87 | L3MBTL1 (0.62) | MEN1KMT2AKCNK9HPSENPC1 | |
| SCHEMBL3660580 | 0.86 | MEN1 (0.62) | MEN1KMT2AKCNK9NPC1RAB9A | |
| SCHEMBL11582597 | 0.85 | L3MBTL1 (0.54) | MEN1KMT2APKML3MBTL1ALDH1A1 | |
| SCHEMBL5925570 | 0.84 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7129217 | 0.83 | PTGS1 (0.57) | MEN1KMT2AKCNK9SMN1; SMN2NR1H4 | |
| SCHEMBL31046595 | 0.83 | AKR1C3 (0.57) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7701421 | 0.83 | AKR1C3 (0.57) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30686768 | 0.82 | MEN1 (0.83) | MEN1KMT2AKCNK9HPSENPC1 | |
| SCHEMBL14195814 | 0.81 | KCNK9 (0.83) | MEN1KMT2AKCNK9HPSENPC1 | |
| SCHEMBL4652364 | 0.81 | MEN1 (0.56) | MEN1KMT2AKCNK9NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049572-A | Leukotriene biosynthesis inhibitors | RIKER LABORATORIES, INC. (US) | 1991-09-17 | — | — | US | claimed |
| EP-0286364-B1 | Substituted Di-t-Butylphenols | RIKER LABORATORIES INC (US) | 1994-07-13 | — | — | EP | disclosed |
| US-5103037-A | Inhibitors of leukotriene biosynthesis; antiallergens | RIKER LABORATORIES, INC. (US) | 1992-04-07 | — | — | US | disclosed |
| US-5049572-A | Leukotriene biosynthesis inhibitors | RIKER LABORATORIES, INC. (US) | 1991-09-17 | — | — | US | disclosed |
| EP-0286364-A2 | Substituted Di-t-Butylphenols | RIKER LABORATORIES, INC. (US) | 1988-10-12 | — | — | EP | disclosed |