Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1903605 | 0.83 | NPC1 (0.46) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL1902888 | 0.80 | ALDH1A1 (0.49) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| Phosphoric Acid SCHEMBL8431601 | 0.79 | PTPN5 (0.41) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| Phosphoric Acid SCHEMBL8431599 | 0.79 | PTPN5 (0.41) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL6064231 | 0.78 | ALDH1A1 (0.40) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| Phosphoric Acid SCHEMBL29128797 | 0.78 | NPC1 (0.45) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL228138 | 0.78 | ALDH1A1 (0.53) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL5080714 | 0.78 | ALDH1A1 (0.57) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL28326671 | 0.78 | ALDH1A1 (0.57) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL30932116 | 0.77 | ALDH1A1 (0.44) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342869-A | Monophosphonate, diphosphonate, phosphonate-phosphonite stabilizers against weathering | SANDOZ LTD. (CH) | 1994-08-30 | — | — | US | disclosed |