Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.55 |
| ▸ | SQLE | Q14534 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417662 | 1.00 | KMT2A (0.61) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL16682277 | 0.91 | KMT2A (0.55) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL28342394 | 0.90 | KMT2A (0.70) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL27437786 | 0.90 | KMT2A (0.70) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL19841923 | 0.79 | KMT2A (0.67) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL3269528 | 0.78 | FNTA (0.54) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL3269523 | 0.78 | FNTA (0.54) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL23802597 | 0.78 | KMT2A (1.00) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| Squalene SCHEMBL890053 | 0.78 | KMT2A (1.00) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL21639794 | 0.78 | KMT2A (1.00) | KMT2AALOX15MAPTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362906-A | Antitumor | MERCK & CO., INC. (US) | 1994-11-08 | — | — | US | disclosed |
| EP-0534546-A1 | Farnesyl pyrophosphate analogs | MERCK & CO. INC. (US) | 1993-03-31 | — | — | EP | disclosed |