Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172389 | 0.87 | NAAA (0.58) | NAAAHTTTSHRHPGDALDH1A1 | |
| SCHEMBL9167102 | 0.84 | NAAA (0.53) | NAAAHTTTSHRALDH1A1ALOX15 | |
| SCHEMBL9549318 | 0.83 | NAAA (0.67) | NAAAHTTTSHRHPGDALDH1A1 | |
| SCHEMBL11089468 | 0.81 | HTT (0.86) | NAAAHTTTSHRHPGDALDH1A1 | |
| SCHEMBL5362359 | 0.81 | HTT (0.86) | NAAAHTTTSHRHPGDALDH1A1 | |
| SCHEMBL9260536 | 0.81 | HTT (0.86) | NAAAHTTTSHRHPGDALDH1A1 | |
| SCHEMBL11078107 | 0.81 | HTT (0.86) | NAAAHTTTSHRHPGDALDH1A1 | |
| SCHEMBL9549393 | 0.81 | NAAA (0.63) | NAAAHTTTSHRHPGDALDH1A1 | |
| SCHEMBL23610299 | 0.79 | HTT (0.75) | NAAAHTTTSHRHPGDALDH1A1 | |
| SCHEMBL986325 | 0.79 | HTT (0.75) | NAAAHTTTSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579066-A2 | N-substituted anilines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-01-19 | — | — | EP | disclosed |