Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 7/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417892 | 0.90 | CYP3A4 (0.41) | CYP3A4TSHR | |
| SCHEMBL9417827 | 0.85 | HTT (0.45) | HTTLTB4RLTB4R2CYP3A4TSHR | |
| SCHEMBL9417757 | 0.85 | LTB4R (0.53) | LTB4RLTB4R2MEN1ALDH1A1CYP3A4 | |
| SCHEMBL9417775 | 0.84 | HTT (0.44) | HTTLTB4RLTB4R2MEN1ALDH1A1 | |
| SCHEMBL9417971 | 0.84 | LTB4R (0.53) | LTB4RLTB4R2MEN1ALDH1A1CYP3A4 | |
| SCHEMBL9417794 | 0.81 | LTB4R (0.44) | HTTLTB4RLTB4R2MEN1ALDH1A1 | |
| SCHEMBL9417877 | 0.81 | LTB4R (0.42) | HTTLTB4RLTB4R2MEN1ALDH1A1 | |
| SCHEMBL9417897 | 0.80 | LTB4R (0.45) | HTTLTB4RLTB4R2MEN1ALDH1A1 | |
| SCHEMBL9417852 | 0.80 | LTB4R (0.43) | HTTLTB4RLTB4R2MEN1ALDH1A1 | |
| SCHEMBL9417879 | 0.80 | LTB4R (0.43) | HTTLTB4RLTB4R2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294613-A | Benzene derivatives of p-substituted ether and acid or ester | ELI LILLY AND COMPANY (US) | 1994-03-15 | — | — | US | disclosed |
| US-5098613-A | Aromatic ethers for treatment of mammals | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4945099-A | LEUKOTRIENE ANTAGONIST | ELI LILLY AND COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0276065-B1 | ANTI-INFLAMMATORY AGENTS | ELI LILLY AND COMPANY (US) | 1990-06-06 | — | — | EP | disclosed |