Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417774 | 0.90 | HTT (0.40) | CYP3A4TSHR | |
| SCHEMBL14641571 | 0.83 | CYP3A4 (0.51) | CYP3A4TSHRLMNAMAPTL3MBTL1 | |
| SCHEMBL10288012 | 0.81 | CYP3A4 (0.43) | CYP3A4TSHRLMNAMAPTL3MBTL1 | |
| SCHEMBL9417823 | 0.80 | CYP3A4 (0.42) | CYP3A4TSHRLMNAMAPTL3MBTL1 | |
| SCHEMBL9417827 | 0.80 | HTT (0.45) | CYP3A4TSHR | |
| SCHEMBL9417947 | 0.79 | CYP3A4 (0.41) | CYP3A4TSHRLMNAMAPTL3MBTL1 | |
| SCHEMBL9417765 | 0.78 | CYP3A4 (0.40) | CYP3A4TSHRLMNASMN1; SMN2 | |
| SCHEMBL24311265 | 0.75 | LMNA (0.37) | LMNAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL24311348 | 0.75 | LMNA (0.40) | LMNAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL9417761 | 0.74 | NR1H4 (0.42) | LMNAMAPTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294613-A | Benzene derivatives of p-substituted ether and acid or ester | ELI LILLY AND COMPANY (US) | 1994-03-15 | — | — | US | disclosed |
| US-5098613-A | Aromatic ethers for treatment of mammals | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4945099-A | LEUKOTRIENE ANTAGONIST | ELI LILLY AND COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0276065-B1 | ANTI-INFLAMMATORY AGENTS | ELI LILLY AND COMPANY (US) | 1990-06-06 | — | — | EP | disclosed |