Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707868 | 0.85 | NPC1 (0.55) | NPC1RAB9AALDH1A1L3MBTL1GLA | |
| SCHEMBL4536987 | 0.82 | RAB9A (0.52) | NPC1RAB9AALDH1A1GLAMAPT | |
| SCHEMBL28568187 | 0.82 | RAB9A (0.49) | NPC1RAB9AALDH1A1L3MBTL1GLA | |
| SCHEMBL11715245 | 0.79 | NPC1 (0.46) | NPC1RAB9AALDH1A1L3MBTL1GLA | |
| SCHEMBL6448403 | 0.78 | NPC1 (0.45) | NPC1RAB9AALDH1A1L3MBTL1GLA | |
| SCHEMBL2882726 | 0.77 | NPC1 (0.58) | NPC1RAB9AALDH1A1L3MBTL1GLA | |
| SCHEMBL3533214 | 0.76 | KDM4E (0.57) | NPC1RAB9AALDH1A1L3MBTL1GLA | |
| SCHEMBL8443182 | 0.75 | ALDH1A1 (0.47) | NPC1RAB9AALDH1A1L3MBTL1GLA | |
| SCHEMBL3787635 | 0.73 | NPC1 (0.44) | NPC1RAB9AALDH1A1L3MBTL1GLA | |
| SCHEMBL2621291 | 0.73 | MAPT (0.70) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6247946-A | — | — | None | — | — | JP | disclosed |
| JP-H06247946-A | PRODUCTION OF 4-OXO-1,3-BENZOXAZINE COMPOUNDS | SHIRATORI SEIYAKU KK | 1994-09-06 | — | — | JP | disclosed |