Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.43 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.42 |
| ▸ | S100A10 | P60903 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887631 | 0.86 | CYP3A4 (0.47) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| SCHEMBL10813732 | 0.86 | CYP3A4 (1.00) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| SCHEMBL9647870 | 0.86 | CYP3A4 (1.00) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| SCHEMBL1098379 | 0.86 | CYP3A4 (1.00) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| SCHEMBL9485453 | 0.86 | CYP3A4 (1.00) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| SCHEMBL9485438 | 0.86 | CYP3A4 (1.00) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| SCHEMBL9649030 | 0.86 | CYP3A4 (1.00) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| 4,4'-Thiodianiline SCHEMBL49068 | 0.86 | CYP3A4 (1.00) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| SCHEMBL9647766 | 0.86 | CYP3A4 (1.00) | CYP3A4MAPK1TSHRMAPTMEN1 | |
| SCHEMBL9649049 | 0.86 | CYP3A4 (1.00) | CYP3A4MAPK1TSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328980-A | Promoters with halothiophenol compounds and polar organic compounds | PHILLIPS PETROLEUM COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| EP-0604778-A2 | Method of preparing poly(arylene sulfide)polymers, polymers, and polymer blends | PHILLIPS PETROLEUM COMPANY (US) | 1994-07-06 | — | — | EP | disclosed |