Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440418 | 0.88 | MAOA (0.50) | CYP3A4NR1H2TSHRMAPK1HPGD | |
| SCHEMBL8148296 | 0.86 | MAOA (0.52) | CYP3A4NR1H2TSHRMAPK1HPGD | |
| SCHEMBL12525121 | 0.86 | MLYCD (0.45) | CYP3A4NR1H2TSHRMAPK1HPGD | |
| SCHEMBL9418092 | 0.86 | CYP3A4 (0.74) | CYP3A4NR1H2TSHRMAPK1HPGD | |
| SCHEMBL9440388 | 0.86 | MEN1 (0.44) | CYP3A4NR1H2TSHRMAPK1DDAH1 | |
| SCHEMBL24413620 | 0.86 | NR1H2 (0.74) | CYP3A4NR1H2TSHRMAPK1HPGD | |
| SCHEMBL8142840 | 0.86 | MAOA (0.52) | CYP3A4NR1H2TSHRMAPK1LMNA | |
| SCHEMBL21763722 | 0.80 | APP (0.61) | APPCA1CA2MEN1KMT2A | |
| SCHEMBL222988 | 0.79 | HSD17B10 (0.44) | CYP3A4TSHRHPGDAPPHDAC8 | |
| SCHEMBL9418083 | 0.78 | TPMT (0.74) | TSHRHPGDLMNAL3MBTL1TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576417-A | Method for synthesizing aromatic polymers | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1996-11-19 | — | — | US | claimed |
| CN-115772103-B | Method for preparing sulfoxide compound by catalytic oxidation of thioether | 华东师范大学 | 2025-04-01 | — | — | CN | disclosed |
| CN-115354350-B | Method for in-situ nitration of electrocatalytic halogenated aromatic hydrocarbon | 平顶山学院 | 2025-02-25 | — | — | CN | disclosed |
| CN-118724774-A | N-O bond guanidine compound, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2024-10-01 | — | — | CN | disclosed |
| CN-114409714-B | Method for synthesizing 1, 3-disubstituted plane chiral metallocene compound | 武汉大学 | 2024-02-06 | — | — | CN | disclosed |
| CN-114729006-A | Cyclic peptide compounds having Kras inhibitory activity | 中外制药株式会社 | 2022-07-08 | — | — | CN | disclosed |
| US-10767013-B2 | Porous/nanoporous PHT | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2020-09-08 | — | — | US | disclosed |
| US-20190135979-A1 | POROUS/NANOPOROUS PHT | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2019-05-09 | — | — | US | disclosed |
| US-7112697-B1 | Methods for formation of aryl-sulfur and aryl-selenium compounds using copper(I) catalysts | UNIVERSITY OF MASSACHUSETTS (US) | 2006-09-26 | — | — | US | disclosed |
| US-6034206-A | POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE | TOSOH CORPORATION (JP) | 2000-03-07 | — | — | US | disclosed |
| US-5576417-A | Method for synthesizing aromatic polymers | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1996-11-19 | — | — | US | disclosed |
| US-5268449-A | Containing arylene sulfide and arylene sulfonate segments | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-07 | — | — | US | disclosed |