Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418108 | 1.00 | SPHK1 (0.40) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL7215017 | 0.91 | SPHK1 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL18124784 | 0.79 | SPHK1 (0.34) | SPHK1MAPTALDH1A1CA2DNM1 | |
| SCHEMBL18124785 | 0.79 | SPHK1 (0.34) | SPHK1MAPTALDH1A1CA2DNM1 | |
| SCHEMBL18125144 | 0.79 | SPHK1 (0.34) | SPHK1MAPTALDH1A1CA2DNM1 | |
| SCHEMBL18124699 | 0.77 | SPHK1 (0.33) | SPHK1ALDH1A1CA2DNM1FDPS | |
| SCHEMBL18923209 | 0.77 | CYP2D6 (0.39) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL21536755 | 0.77 | ALDH1A1 (0.37) | LMNACYP3A4ALDH1A1CA2DNM1 | |
| SCHEMBL22539049 | 0.77 | ALDH1A1 (0.32) | CETPALDH1A1CA2DNM1FDPS | |
| SCHEMBL8180450 | 0.77 | CYP2D6 (0.39) | SPHK1CYP2D6GMNNLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6321826-A | — | — | None | — | — | JP | disclosed |
| JP-H06321826-A | 1,1,1-TRIFLUOROALKAN-2,3-DIOL AND ITS PRODUCTION | TOAGOSEI CHEM IND CO LTD | 1994-11-22 | — | — | JP | disclosed |