Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418110 | 0.91 | SPHK1 (0.40) | SPHK1CYP2D6LMNAMAPTGMNN | |
| SCHEMBL9418108 | 0.91 | SPHK1 (0.40) | SPHK1CYP2D6LMNAMAPTGMNN | |
| SCHEMBL19997564 | 0.83 | GPR84 (0.42) | SPHK1CYP2D6LMNAMAPTGMNN | |
| SCHEMBL16078656 | 0.78 | SPHK1 (0.52) | SPHK1CYP2D6LMNAMAPTGMNN | |
| SCHEMBL16078618 | 0.78 | SPHK1 (0.52) | SPHK1CYP2D6LMNAMAPTGMNN | |
| SCHEMBL16078696 | 0.78 | SPHK1 (0.52) | SPHK1CYP2D6LMNAMAPTGMNN | |
| SCHEMBL16078686 | 0.78 | SPHK1 (0.52) | SPHK1CYP2D6LMNAMAPTGMNN | |
| SCHEMBL22805001 | 0.78 | SPHK1 (0.68) | SPHK1CYP2D6LMNAMAPTGMNN | |
| SCHEMBL22804794 | 0.78 | SPHK1 (0.68) | SPHK1CYP2D6LMNAMAPTGMNN | |
| SCHEMBL22805047 | 0.78 | SPHK1 (0.68) | SPHK1CYP2D6LMNAMAPTGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613358-B2 | Contacting an organic solvent with co-dissolved a biocompatible polymer and a hydrophobic ion pair complex of an amphiphilic material and pharmaceutical with a compressed antisolvent fluid | ENDO PHARMACEUTICALS, INC. | 2003-09-02 | — | — | US | disclosed |
| US-20020132007-A1 | Sustainded-release composition including amorphous polymer | UNIVERSITY TECHNOLOGY CORPORATION | 2002-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020132007-A1 | Sustainded-release composition including amorphous polymer | CHERP, ATP2A1, ATP2A3 | SPHK1 3348/4885CYP2D6 2555/4885LMNA 1490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.