Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | UNG | P13051 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018938 | 0.82 | ACHE (0.62) | CA12CA1CA2CA6CA9 | |
| SCHEMBL14740775 | 0.81 | CA12 (0.50) | CA12CA1CA2CA6CA9 | |
| Hydrochloric Acid SCHEMBL10926742 | 0.81 | ACHE (0.61) | CA12CA1CA2CA6CA9 | |
| SCHEMBL28678908 | 0.78 | CA12 (0.56) | CA12CA1CA2CA6CA9 | |
| SCHEMBL2786186 | 0.76 | HPGD (0.65) | CA12CA1CA2CA6CA9 | |
| SCHEMBL10476991 | 0.75 | KMO (0.53) | CA12CA1CA2CA6CA9 | |
| SCHEMBL14880008 | 0.74 | CA12 (0.47) | CA12CA1CA2CA6CA9 | |
| SCHEMBL20383105 | 0.74 | AKR1B1 (0.47) | AKR1C3HPGDHSD17B10CYP1A2KMT2A | |
| Isophthalic Acid SCHEMBL29023597 | 0.73 | CA12 (0.60) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL30529662 | 0.73 | CA12 (0.65) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386549-B1 | Aromatic polyester-siloxane block copolymers and method for making | GEN ELECTRIC (US) | 1994-02-09 | — | — | EP | disclosed |
| EP-0386549-A2 | Aromatic polyester-siloxane block copolymers and method for making | GENERAL ELECTRIC COMPANY (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4945147-A | MOLDING MATERIALS, FIREPROOF | GENERAL ELECTRIC COMPANY (US) | 1990-07-31 | — | — | US | disclosed |