Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596358 | 0.81 | THRB (0.49) | THRATHRBKDM4ELMNAHSD17B10 | |
| SCHEMBL9326980 | 0.78 | THRB (0.40) | THRATHRBKDM4ELMNAHCAR2 | |
| SCHEMBL344077 | 0.78 | THRB (0.47) | THRATHRBKDM4ELMNAHSD17B10 | |
| SCHEMBL7523065 | 0.78 | THRB (0.47) | THRATHRBKDM4ELMNAALDH1A1 | |
| SCHEMBL28839147 | 0.77 | THRB (0.41) | THRATHRBKDM4ELMNAHCAR2 | |
| SCHEMBL28297685 | 0.77 | THRB (0.52) | THRATHRBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10426925 | 0.75 | THRB (0.42) | THRATHRBLMNAALDH1A1HPGD | |
| SCHEMBL21030277 | 0.74 | THRB (0.44) | THRATHRBKDM4ELMNAHSD17B10 | |
| SCHEMBL29413361 | 0.73 | THRB (0.56) | THRATHRBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3841280 | 0.73 | THRB (0.56) | THRATHRBKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289797-B1 | Contact lens material | KUREHA CHEMICAL IND CO LTD (JP) | 1994-11-02 | — | — | EP | disclosed |
| EP-0289797-A2 | Contact lens material | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-11-09 | — | — | EP | disclosed |