Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10426925 | 0.80 | THRB (0.42) | THRBTHRACYP2C19HPGDL3MBTL1 | |
| SCHEMBL9418355 | 0.77 | THRA (0.42) | THRBTHRACYP2D6CYP2C19HCAR2 | |
| SCHEMBL4596358 | 0.76 | THRB (0.49) | THRBTHRACYP2C19HPGDKDM4E | |
| SCHEMBL21030277 | 0.76 | THRB (0.44) | THRBTHRACYP2C19HPGDKDM4E | |
| SCHEMBL28839146 | 0.75 | THRB (0.43) | THRBTHRATYRCYP2D6CYP2C19 | |
| SCHEMBL9326980 | 0.75 | THRB (0.40) | THRBTHRACYP2C19HCAR2HPGD | |
| SCHEMBL31295365 | 0.74 | HSD17B10 (0.45) | THRBTHRAHPGDKDM4EMAPT | |
| SCHEMBL8070515 | 0.74 | HSD17B10 (0.45) | THRBTHRAHPGDKDM4EMAPT | |
| SCHEMBL344077 | 0.74 | THRB (0.47) | THRBTHRACYP2C19HPGDKDM4E | |
| SCHEMBL7523065 | 0.74 | THRB (0.47) | THRBTHRACYP2C19HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232715-B | Methacrylic resin composition, formed body, film and polarization plates | 株式会社可乐丽 | 2018-06-15 | — | — | CN | disclosed |
| CN-107428860-A | Method for producing (meth) acrylic resin composition | 株式会社可乐丽 | 2017-12-01 | — | — | CN | disclosed |
| CN-106414599-A | Methacrylic resin composition | 株式会社可乐丽 | 2017-02-15 | — | — | CN | disclosed |