Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1109621 | 0.83 | CYP1A2 (0.48) | CYP1A2KDM4ELMNASMN1; SMN2TSHR | |
| SCHEMBL29376964 | 0.83 | CYP1A2 (0.48) | CYP1A2KDM4ELMNASMN1; SMN2TSHR | |
| SCHEMBL8979696 | 0.79 | ATM (0.36) | LMNATSHRABCB1CYP2D6TDP1 | |
| SCHEMBL9418361 | 0.77 | TSHR (0.38) | CYP1A2KDM4ELMNASMN1; SMN2TSHR | |
| SCHEMBL25436245 | 0.76 | ATM (0.40) | ALDH1A1TDP1ATMKMT2A | |
| SCHEMBL5084756 | 0.74 | KDM4E (0.42) | CYP1A2KDM4ELMNASMN1; SMN2TSHR | |
| SCHEMBL21238283 | 0.73 | LMNA (0.35) | CYP1A2KDM4ELMNASMN1; SMN2CYP2D6 | |
| SCHEMBL25793145 | 0.73 | LMNA (0.48) | CYP1A2KDM4ELMNASMN1; SMN2TSHR | |
| SCHEMBL12416575 | 0.72 | CYP1A2 (0.52) | CYP1A2KDM4ELMNASMN1; SMN2TSHR | |
| SCHEMBL10715704 | 0.72 | TSHR (0.41) | CYP1A2KDM4ELMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289797-B1 | Contact lens material | KUREHA CHEMICAL IND CO LTD (JP) | 1994-11-02 | — | — | EP | disclosed |
| EP-0289797-A2 | Contact lens material | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-11-09 | — | — | EP | disclosed |