Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214664 | 0.84 | VDR (0.31) | LMNATSHR | |
| SCHEMBL9064851 | 0.84 | ATM (0.40) | ATMTDP1LMNAPTPN1ELANE | |
| SCHEMBL9065256 | 0.84 | THRB (0.38) | ATMTDP1LMNAPTPN1TSHR | |
| SCHEMBL25436245 | 0.82 | ATM (0.40) | ATMTDP1PTPN1ELANEMAPK1 | |
| SCHEMBL869200 | 0.81 | LMNA (0.34) | LMNAPTPN1MAPT | |
| SCHEMBL9418364 | 0.79 | CYP1A2 (0.37) | ATMTDP1LMNATSHRMAPT | |
| SCHEMBL10483956 | 0.79 | PPARG (0.35) | LMNAPTPN1ABCB1 | |
| SCHEMBL8922974 | 0.79 | LMNA (0.37) | LMNAPTPN1ELANETSHRMAPK1 | |
| SCHEMBL9336589 | 0.78 | TDP1 (0.39) | ATMTDP1ELANEMAPTMAPK1 | |
| SCHEMBL346348 | 0.77 | ELANE (0.37) | ATMTDP1LMNAELANETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9132068-B2 | Dental composite restorative material | TOKUYAMA DENTAL CORPORATION (JP) | 2015-09-15 | — | — | US | disclosed |
| US-20130096226-A1 | DENTAL COMPOSITE RESTORATIVE MATERIAL | TOKUYAMA DENTAL CORPORATION (JP) | 2013-04-18 | — | — | US | disclosed |
| EP-0540043-B1 | Cast resin for optical use | NOF CORP (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0540003-B1 | Cast resin for optical use | NOF CORP (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5340893-A | Blend containing an allyl containing polyester | NOF CORPORATION (JP) | 1994-08-23 | — | — | US | disclosed |
| US-5336743-A | Diallylphthalate component and an alkylene bis-allylcarbonate component | NOF CORPORATION (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0540003-A1 | Cast resin for optical use | NOF CORPORATION (JP) | 1993-05-05 | — | — | EP | disclosed |
| EP-0540043-A1 | Cast resin for optical use | NOF CORPORATION (JP) | 1993-05-05 | — | — | EP | disclosed |