Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418494 | 1.00 | CYP19A1 (0.40) | CYP19A1CA1CA2CA4LMNA | |
| SCHEMBL4166949 | 0.92 | KMT2A (0.41) | CYP19A1CA1CA2CA4LMNA | |
| SCHEMBL3682541 | 0.74 | CYP19A1 (0.35) | CYP19A1LMNATSHRKMT2AMEN1 | |
| SCHEMBL13261222 | 0.72 | CYP19A1 (0.53) | CYP19A1LMNATSHRHSD17B3 | |
| SCHEMBL103226 | 0.72 | CYP19A1 (0.53) | CYP19A1LMNATSHRHSD17B3 | |
| SCHEMBL178322 | 0.72 | CYP19A1 (0.53) | CYP19A1LMNATSHRHSD17B3 | |
| SCHEMBL10646120 | 0.72 | CYP19A1 (0.43) | CYP19A1LMNATSHRKDM4E | |
| SCHEMBL3146702 | 0.72 | PIK3CA (0.42) | CYP19A1CA1CA2CA4TSHR | |
| SCHEMBL2690489 | 0.71 | CA1 (0.43) | CYP19A1CA1CA2CA4KMT2A | |
| SCHEMBL15308966 | 0.71 | LMNA (0.38) | CYP19A1LMNATSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360127-B1 | Oxygenated bicyclic derivatives and their use as perfuming ingredients | FIRMENICH & CIE (CH) | 1994-12-07 | — | — | EP | claimed |
| EP-0360127-A2 | Oxygenated bicyclic derivatives and their use as perfuming ingredients | FIRMENICH SA (CH) | 1990-03-28 | — | — | EP | claimed |
| EP-0360127-B1 | Oxygenated bicyclic derivatives and their use as perfuming ingredients | FIRMENICH & CIE (CH) | 1994-12-07 | — | — | EP | disclosed |