Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.49 |
| ▸ | MTOR | P42345 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619652 | 0.95 | KDM4E (0.48) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL28640929 | 0.94 | KDM4E (0.59) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL28630449 | 0.92 | ALDH1A1 (0.62) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL8973821 | 0.88 | HTT (0.63) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL9418611 | 0.85 | HTT (0.61) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL29274357 | 0.78 | HRH1 (0.56) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL7531287 | 0.78 | ALDH1A1 (0.64) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL1443593 | 0.77 | PIK3CA (0.61) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL9619196 | 0.77 | KDM4E (0.58) | HTTKDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL1308905 | 0.77 | MAPT (0.61) | HTTKDM4EMAPK1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088824-A | Preparation method of alpha-1, 3, 5-triazine thioketone compound | 浙江工业大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-113292509-B | Aromatic thioether compound and preparation method and application thereof | 浙江工业大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-113292509-A | Aromatic thioether compound and preparation method and application thereof | 浙江工业大学 | 2021-08-24 | — | — | CN | disclosed |