Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 12/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.53 |
| ▸ | RPA1 | P27694 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418691 | 0.84 | RXRA (0.53) | MARS1RXRANR1H2NR1H3SMN1; SMN2 | |
| SCHEMBL341019 | 0.83 | RXRA (0.62) | MARS1RXRANR1H2NR1H3RPA1 | |
| SCHEMBL29419072 | 0.83 | RXRA (0.62) | MARS1RXRANR1H2NR1H3RPA1 | |
| SCHEMBL9418677 | 0.82 | MARS1 (0.72) | MARS1RXRANR1H2NR1H3RPA1 | |
| SCHEMBL10388627 | 0.81 | RXRA (0.52) | RXRANR1H2NR1H3SMN1; SMN2MEN1 | |
| SCHEMBL2982610 | 0.80 | RPA1 (0.73) | MARS1RPA1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31130354 | 0.79 | SLC16A3 (0.59) | MARS1RXRANR1H2NR1H3RPA1 | |
| SCHEMBL31130190 | 0.79 | SLC16A3 (0.59) | MARS1RXRANR1H2NR1H3SMN1; SMN2 | |
| SCHEMBL15229876 | 0.78 | RXRA (0.52) | MARS1RXRANR1H2NR1H3SMN1; SMN2 | |
| SCHEMBL12000521 | 0.78 | KMT2A (0.66) | MARS1RPA1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558448-A1 | 1,5-diphenylpyrazole-3-carboxylic acid derivatives as antidotes for sulfonylurea herbicides | CIBA-GEIGY AG (CH) | 1993-09-01 | — | — | EP | claimed |
| US-5371060-A | PREFERENTIAL WEED CONTROL | CIBA-GEIGY CORPORATION (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0558448-A1 | 1,5-diphenylpyrazole-3-carboxylic acid derivatives as antidotes for sulfonylurea herbicides | CIBA-GEIGY AG (CH) | 1993-09-01 | — | — | EP | disclosed |