Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.34 |
| ▸ | ITGAL | P20701 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418918 | 1.00 | ITGB2 (0.34) | ITGB2ICAM1ITGALESR1CA12 | |
| SCHEMBL31042648 | 1.00 | ITGB2 (0.34) | ITGB2ICAM1ITGALESR1CA12 | |
| SCHEMBL8896559 | 0.88 | ITGB2 (0.38) | ITGB2ICAM1ITGALESR1CA12 | |
| SCHEMBL872308 | 0.81 | — | — | |
| SCHEMBL9146075 | 0.81 | — | — | |
| SCHEMBL4324456 | 0.79 | CA12 (0.32) | CA12CA1CA2CA9 | |
| SCHEMBL5176137 | 0.78 | CHRNB2 (0.36) | ESR1 | |
| SCHEMBL5175649 | 0.78 | CHRNB2 (0.36) | ESR1 | |
| SCHEMBL3094719 | 0.77 | CA12 (0.45) | CA12CA1CA2CA9 | |
| SCHEMBL3103277 | 0.77 | CA12 (0.45) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355122-B1 | COMPOSITIONS OF POLYPHENYLENE OXIDES AND THERMOPLASTIC POLYMERS | ALLIED SIGNAL INC (US) | 1994-07-13 | — | — | EP | disclosed |
| US-5162440-A | Molding materials with impact resistance | ALLIED-SIGNAL INC. (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0355122-A1 | COMPOSITIONS OF POLYPHENYLENE OXIDES AND THERMOPLASTIC POLYMERS. | ALLIED SIGNAL INC (US) | 1990-02-28 | — | — | EP | disclosed |
| WO-1988008433-A1 | COMPOSITIONS OF POLYPHENYLENE OXIDES AND THERMOPLASTIC POLYMERS | ALLIED-SIGNAL INC. (US) | 1988-11-03 | — | — | WO | disclosed |