SCHEMBL5175649

SCHEMBL5175649

CN(CCO)C(=O)/C=C\C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36
CASP1 P29466 1/20 0.34
ESR1 P03372 1/20 0.34
MAPT P10636 1/20 0.33
CNR1 P21554 1/20 0.33
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5176137 1.00 CHRNB2 (0.36) CHRNB2CHRNB4CHRNA3CHRNA4CASP1
SCHEMBL5175654 0.81 TSHR (0.39) CHRNB2CHRNB4CHRNA3CHRNA4CASP1
SCHEMBL5176139 0.81 TSHR (0.39) CHRNB2CHRNB4CHRNA3CHRNA4CASP1
SCHEMBL4859222 0.81 TSHR (0.39) CHRNB2CHRNB4CHRNA3CHRNA4CASP1
SCHEMBL31042648 0.78 ITGB2 (0.34) ESR1
SCHEMBL9418918 0.78 ITGB2 (0.34) ESR1
SCHEMBL9418921 0.78 ITGB2 (0.34) ESR1
SCHEMBL5174647 0.78 CHRNB2 (0.38) CHRNB2CHRNB4CHRNA3CHRNA4CASP1
SCHEMBL5174650 0.78 CHRNB2 (0.38) CHRNB2CHRNB4CHRNA3CHRNA4CASP1
SCHEMBL2128011 0.77 EPHX2 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1281516-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2007-12-19 EP disclosed
EP-1602481-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-05-30 EP disclosed
EP-1203659-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 EP disclosed
EP-1602481-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-12-07 EP disclosed
US-6951171-B2 Using graft polymer on etched or anodized aluminum substrate FUJI PHOTO FILM CO., LTD. (JP) 2005-10-04 US disclosed
EP-1371500-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-09-28 EP disclosed
US-6939658-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-09-06 US disclosed
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 EP disclosed
US-6824946-B2 SUPPORT WITH HYDROPHILIC SURFACE HAVING AN IMAGE-FORMING LAYER CONTAINING A HYDROPHOBIC HIGH MOLECULAR COMPOUND WITH SALTS OF SULFONATES AND CARBOXYLS WITH IODONIUM, SULFONIUM OR DIAZONIUM IONS FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 US disclosed
EP-1031414-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-06-16 EP disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
US-20020068241-A1 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-06-06 US disclosed
EP-1203659-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 EP disclosed
US-6379863-B1 LAMINATING HYDROPHOBIC POLYMER ON SUBSTRATE; HEATING TO MAKE HYDROPHILIC; DURABILITY; REDUCED BLEMISHES; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 2002-04-30 US disclosed
EP-1136281-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 EP disclosed
US-6153352-A OBTAINED BY LAMINATING ON A SUBSTRATE A LAYER OF HYDROPHOBIC POLYMER AND A LAYER OF HYDROPHILIC POLYMER FUJI PHOTO FILM CO., LTD. (JP) 2000-11-28 US disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 EP disclosed
EP-0922570-A2 Planographic printing plate precursor and a method for producing a planographic plate Fuji Photo Film Co., Ltd. (JP) 1999-06-16 EP disclosed
US-4212982-A Polyisocyanates with at least one hydantoin or thiohydantoin ring substituted by carboxylic acid amide groups BAYER AKTIENGESELLSCHAFT (DE) 1980-07-15 US disclosed