Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419161 | 0.78 | IDO1 (0.41) | IDO1TAAR1NR3C1LMNASMN1; SMN2 | |
| SCHEMBL73408 | 0.76 | IDO1 (0.50) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL28937583 | 0.73 | IDO1 (0.44) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL1885793 | 0.72 | IDO1 (0.46) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| Clortermine SCHEMBL164137 | 0.72 | PNMT (0.52) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL13509534 | 0.72 | IDO1 (0.46) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| Clortermine SCHEMBL30295323 | 0.72 | PNMT (0.52) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL28872674 | 0.72 | IDO1 (0.42) | IDO1PNMTTAAR1NR3C1NR3C2 | |
| SCHEMBL19779343 | 0.71 | IDO1 (0.36) | IDO1PNMTTAAR1NR3C1NR3C2 | |
| SCHEMBL19779342 | 0.71 | IDO1 (0.36) | IDO1PNMTTAAR1NR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446301-B1 | PREPARATION OF BIARYL COMPOUNDS | EASTMAN CHEM CO (US) | 1994-11-23 | — | — | EP | claimed |
| EP-0440737-A1 | PREPARATION OF BIARYL COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1991-08-14 | — | — | EP | claimed |
| EP-0376856-A1 | Preparation of biaryl compounds | EASTMAN KODAK COMPANY (US) | 1990-07-04 | — | — | EP | claimed |
| WO-1990004577-A1 | PREPARATION OF BIARYL COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1990-05-03 | — | — | WO | claimed |
| EP-0366573-A1 | Preparation of biaryl compounds | EASTMAN CHEMICAL COMPANY (US) | 1990-05-02 | — | — | EP | claimed |
| US-4912276-A | Preparation of biaryl compounds | EASTMAN KODAK COMPANY (US) | 1990-03-27 | — | — | US | claimed |
| US-10703959-B2 | Functionalized silicate nanoparticle composition, removing and exfoliating asphaltenes with same | BAKER HUGHES, A GE COMPANY, LLC (US) | 2020-07-07 | — | — | US | disclosed |
| US-20170247599-A1 | FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME | BAKER HUGHES INCORPORATED | 2017-08-31 | — | — | US | disclosed |
| US-9683163-B2 | Functionalized silicate nanoparticle composition, removing and exfoliating asphaltenes with same | BAKER HUGHES INCORPORATED (US) | 2017-06-20 | — | — | US | disclosed |
| WO-2016149454-A1 | FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME | BAKER HUGHES INCORPORATED (US) | 2016-09-22 | — | — | WO | disclosed |
| US-20150191646-A1 | FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME | BAKER HUGHES INCORPORATED (US) | 2015-07-09 | — | — | US | disclosed |
| US-9012377-B2 | Functionalized silicate nanoparticle composition, removing and exfoliating asphaltenes with same | BAKER HUGHES INCORPORATED (US) | 2015-04-21 | — | — | US | disclosed |
| US-20140187449-A1 | FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME | BAKER HUGHES INCORPORATED (US) | 2014-07-03 | — | — | US | disclosed |
| US-5021380-A | Contacting nickel/II/ compound with organophosphine and bidentate nitrogen-containing ligands and tertiary-alkyl organometallic compound in nonpolar ether solvent to form nickel/0/ species | EASTMAN KODAK COMPANY (US) | 1991-06-04 | — | — | US | disclosed |
| EP-0376856-A1 | Preparation of biaryl compounds | EASTMAN KODAK COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |
| US-4939309-A | REACTING ARYL HALIDE WITH NICKEL-ORGANOPHOSPHINE-ORGANOMETAL-LIC-BIDENTATE LIGAND CATALYST | EASTMAN KODAK COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| WO-1990006295-A1 | PREPARATION OF BIARYL COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1990-06-14 | — | — | WO | disclosed |
| EP-0366573-A1 | Preparation of biaryl compounds | EASTMAN CHEMICAL COMPANY (US) | 1990-05-02 | — | — | EP | disclosed |
| US-4916227-A | From aromatic halide using coordinating catalyst containing nickel, phosphorus containing ligand, and reducing metal | EASTMAN KODAK COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| US-4912276-A | Preparation of biaryl compounds | EASTMAN KODAK COMPANY (US) | 1990-03-27 | — | — | US | disclosed |