SCHEMBL9419161

SCHEMBL9419161

COC(C)(Cc1ccccc1Br)OC(C)(Cc1ccccc1Br)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.41
TAAR1 Q96RJ0 3/20 0.39
NR3C1 P04150 1/20 0.39
RIPK1 Q13546 2/20 0.37
TSHR P16473 3/20 0.36
PYCR1 P32322 1/20 0.34
ALDH1A1 P00352 3/20 0.33
HTT P42858 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
NFKB1 P19838 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3059868 0.92 IDO1 (0.44) IDO1TAAR1NR3C1RIPK1TSHR
SCHEMBL9419183 0.78 IDO1 (0.41) IDO1TAAR1NR3C1PYCR1NPC1
SCHEMBL1691374 0.76 RIPK1 (0.47) IDO1TAAR1NR3C1RIPK1TSHR
SCHEMBL1567091 0.76 IDO1 (0.52) IDO1TAAR1RIPK1TSHRPYCR1
SCHEMBL2401345 0.72 RIPK1 (0.45) IDO1TAAR1NR3C1RIPK1TSHR
SCHEMBL30388724 0.72 RIPK1 (0.45) IDO1TAAR1NR3C1RIPK1TSHR
SCHEMBL18623577 0.72 TAAR1 (0.44) IDO1TAAR1NR3C1RIPK1TSHR
SCHEMBL15638695 0.72 TAAR1 (0.50) IDO1TAAR1NR3C1RIPK1TSHR
SCHEMBL28240019 0.71 TAAR1 (0.41) IDO1TAAR1NR3C1RIPK1TSHR
SCHEMBL11970972 0.71 RIPK1 (0.47) IDO1TAAR1NR3C1RIPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0440737-A1 PREPARATION OF BIARYL COMPOUNDS EASTMAN KODAK COMPANY (US) 1991-08-14 EP claimed
WO-1990004577-A1 PREPARATION OF BIARYL COMPOUNDS EASTMAN KODAK COMPANY (US) 1990-05-03 WO claimed
EP-0366573-A1 Preparation of biaryl compounds EASTMAN CHEMICAL COMPANY (US) 1990-05-02 EP claimed
US-4912276-A Preparation of biaryl compounds EASTMAN KODAK COMPANY (US) 1990-03-27 US claimed
US-10703959-B2 Functionalized silicate nanoparticle composition, removing and exfoliating asphaltenes with same BAKER HUGHES, A GE COMPANY, LLC (US) 2020-07-07 US disclosed
US-20170247599-A1 FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME BAKER HUGHES INCORPORATED 2017-08-31 US disclosed
US-9683163-B2 Functionalized silicate nanoparticle composition, removing and exfoliating asphaltenes with same BAKER HUGHES INCORPORATED (US) 2017-06-20 US disclosed
WO-2016149454-A1 FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME BAKER HUGHES INCORPORATED (US) 2016-09-22 WO disclosed
US-20150191646-A1 FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME BAKER HUGHES INCORPORATED (US) 2015-07-09 US disclosed
US-9012377-B2 Functionalized silicate nanoparticle composition, removing and exfoliating asphaltenes with same BAKER HUGHES INCORPORATED (US) 2015-04-21 US disclosed
WO-2014106007-A1 FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME BAKER HUGHES INCORPORATED (US) 2014-07-03 WO disclosed
US-20140187449-A1 FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME BAKER HUGHES INCORPORATED (US) 2014-07-03 US disclosed
US-5021380-A Contacting nickel/II/ compound with organophosphine and bidentate nitrogen-containing ligands and tertiary-alkyl organometallic compound in nonpolar ether solvent to form nickel/0/ species EASTMAN KODAK COMPANY (US) 1991-06-04 US disclosed
EP-0376856-A1 Preparation of biaryl compounds EASTMAN KODAK COMPANY (US) 1990-07-04 EP disclosed
US-4939309-A REACTING ARYL HALIDE WITH NICKEL-ORGANOPHOSPHINE-ORGANOMETAL-LIC-BIDENTATE LIGAND CATALYST EASTMAN KODAK COMPANY (US) 1990-07-03 US disclosed
WO-1990006295-A1 PREPARATION OF BIARYL COMPOUNDS EASTMAN KODAK COMPANY (US) 1990-06-14 WO disclosed
WO-1990004577-A1 PREPARATION OF BIARYL COMPOUNDS EASTMAN KODAK COMPANY (US) 1990-05-03 WO disclosed
EP-0366573-A1 Preparation of biaryl compounds EASTMAN CHEMICAL COMPANY (US) 1990-05-02 EP disclosed
US-4916227-A From aromatic halide using coordinating catalyst containing nickel, phosphorus containing ligand, and reducing metal EASTMAN KODAK COMPANY (US) 1990-04-10 US disclosed
US-4912276-A Preparation of biaryl compounds EASTMAN KODAK COMPANY (US) 1990-03-27 US disclosed