SCHEMBL9419337

SCHEMBL9419337

C=C(CCCCCCC)c1ccc(I)cc1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 6/20 0.43
THRA P10827 3/20 0.39
THRB P10828 3/20 0.39
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
FOLH1 Q04609 2/20 0.37
GAA P10253 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28209780 0.83 HSD17B3 (0.62) HSD17B3ESR1ESR2
SCHEMBL2010661 0.83 L3MBTL1 (0.49) HSD17B3THRATHRBCES2CES1
SCHEMBL27944125 0.83 HSD17B3 (0.62) HSD17B3ESR1ESR2
SCHEMBL23891539 0.81 GAA (0.54) HSD17B3GAA
SCHEMBL11412668 0.81 CES2 (0.58) CES2CES1
SCHEMBL19042193 0.81 L3MBTL1 (0.46) HSD17B3THRATHRBCES2CES1
SCHEMBL29827 0.81 CES2 (0.58) CES2CES1
SCHEMBL10625164 0.81 CES2 (0.58) CES2CES1
SCHEMBL465114 0.81 CES2 (0.58) CES2CES1
SCHEMBL7796974 0.81 CES2 (0.58) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609589-A2 Compositions of alkylbenzenes in film-forming materials for visualization of the gastrointestinal tract NYCOMED IMAGING AS (NO) 1994-08-10 EP disclosed