Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14516277 | 0.95 | NR1I2 (0.41) | NR1I2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18965267 | 0.91 | NR1I2 (0.41) | NR1I2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL22166101 | 0.91 | NR1I2 (0.41) | NR1I2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18885123 | 0.91 | NR1I2 (0.41) | NR1I2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL19788245 | 0.91 | NR1I2 (0.41) | NR1I2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28774586 | 0.91 | NR1I2 (0.41) | NR1I2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL27408998 | 0.89 | NR1I2 (0.40) | NR1I2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL20760340 | 0.88 | NR1I2 (0.39) | NR1I2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13848615 | 0.87 | CHRNB2 (0.36) | NR1I2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL16432014 | 0.84 | NR1I2 (0.35) | NR1I2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10980816-B2 | Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof | SANOFI (FR) | 2021-04-20 | — | — | US | disclosed |
| US-20200323874-A1 | NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2020-10-15 | — | — | US | disclosed |
| EP-3192792-A1 | AMINOSULFONYL COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Suzhou Vigonvita Life Sciences Co., Ltd. (CN) | 2017-07-19 | — | — | EP | disclosed |
| US-20110001905-A1 | TRANSPARENT THIN-FILM ELECTRODE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-0793900-B1 | FABRICATION OF AN ELECTROLUMINESCENT DEVICE | FORSKARPATENT I LINKOEPING AB (SE) | 2001-10-04 | — | — | EP | disclosed |
| US-5932965-A | Electroluminescent device and a method for fabricating an electroluminescent device | FORSKARPATENT I LINKOPING AB (SE) | 1999-08-03 | — | — | US | disclosed |
| EP-0793900-A1 | ELECTROLUMINESCENT DEVICE AND A WAY TO FABRICATE IT | Forskarpatent i Linköping AB (SE) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996003015-A1 | ELECTROLUMINESCENT DEVICE AND A WAY TO FABRICATE IT | FORSKARPATENT I LINKÖPING AB (SE) | 1996-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200323874-A1 | NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | DPYD, TYMP, DHFR | NR1I2 828/4885CHRNB2 3893/4885CHRNB4 4569/4885 |
| US-10980816-B2 | Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof | DPYD, TYMP, DHFR | NR1I2 846/4885CHRNB2 4073/4885CHRNB4 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.