Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871963 | 0.91 | PPARG (0.48) | PPARGEPHX2PPARAALDH1A1HPGD | |
| SCHEMBL19502687 | 0.89 | ALDH1A1 (0.47) | PPARGEPHX2PPARAALDH1A1MEN1 | |
| SCHEMBL11983359 | 0.84 | PPARG (0.50) | PPARGEPHX2PPARAALDH1A1HPGD | |
| SCHEMBL9419792 | 0.84 | PPARG (0.64) | PPARGEPHX2PPARAALDH1A1HPGD | |
| SCHEMBL7384644 | 0.82 | PPARG (0.57) | PPARGEPHX2PPARAALDH1A1HPGD | |
| SCHEMBL1582641 | 0.81 | EPHX2 (0.47) | PPARGEPHX2PPARAALDH1A1HPGD | |
| SCHEMBL7438291 | 0.80 | PPARA (0.40) | PPARGEPHX2PPARAALDH1A1HPGD | |
| SCHEMBL1582617 | 0.79 | KMT2A (0.58) | PPARGPPARAALDH1A1KMT2A | |
| SCHEMBL7621562 | 0.79 | PPARG (0.47) | PPARGPPARAALDH1A1HPGDHTT | |
| SCHEMBL3555234 | 0.77 | CYP1A2 (0.64) | PPARGEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5329033-A | Metallocene catalyst, indene containing ligands, alumoxane cocatalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| US-5278264-A | Catalytic polymerizing in presence of a transition metal metallocene | HOECHST AG (DE) | 1994-01-11 | — | — | US | disclosed |