SCHEMBL9419949

SCHEMBL9419949

C=CCOC(=O)c1ccc(OC)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
NPC1 O15118 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
KDM4E B2RXH2 1/20 0.56
HSP90AA1 P07900 1/20 0.56
RXFP1 Q9HBX9 1/20 0.56
PKM P14618 1/20 0.55
SNCA P37840 1/20 0.55
ESR2 Q92731 1/20 0.54
CYP3A4 P08684 2/20 0.51
MAPT P10636 2/20 0.51
RAB9A P51151 2/20 0.51
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
ADRB2 P07550 2/20 0.49
ADRB1 P08588 2/20 0.49
ADRB3 P13945 2/20 0.49
APOBEC3A P31941 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL175786 0.87 SNCA (0.67) CA1CA2KDM4ESNCAESR2
SCHEMBL2705494 0.86 SNCA (0.58) CA1CA2NPC1SMN1; SMN2KDM4E
SCHEMBL9359957 0.86 SNCA (0.58) NPC1SMN1; SMN2KDM4EHSP90AA1RXFP1
SCHEMBL20481860 0.84 SNCA (0.56) NPC1SMN1; SMN2KDM4EHSP90AA1RXFP1
SCHEMBL19892096 0.84 ADRB2 (0.59) CA1CA2NPC1SMN1; SMN2SNCA
SCHEMBL1932609 0.84 CA1 (0.58) CA1CA2NPC1SMN1; SMN2KDM4E
SCHEMBL24370251 0.83 MAPT (0.56) CA1CA2NPC1SMN1; SMN2PKM
SCHEMBL7667194 0.83 CES2 (0.56) CA1CA2NPC1SMN1; SMN2KDM4E
SCHEMBL11875502 0.83 MAPT (0.56) NPC1SMN1; SMN2PKMSNCACYP3A4
SCHEMBL9270334 0.82 SNCA (0.58) CA1CA2NPC1KDM4ESNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106588644-B A kind of synthetic method of carboxylic acid ester compound 杭州师范大学 2019-03-29 CN disclosed
CN-106588644-A Synthesis method of carboxylic ester compound 杭州师范大学 2017-04-26 CN disclosed
EP-0392514-B1 Organic glass with high refractive index DAISO CO LTD (JP) 1994-10-12 EP disclosed
US-5051488-A A copolymer of diallyl isophthalate, allyl benzoate or methallyl benzoate and a diester of maleic acid DAISO CO., LTD. (JP) 1991-09-24 US disclosed