Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419959 | 0.93 | HTR7 (0.39) | HTR7HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL5175215 | 0.77 | ALOX5AP (0.44) | HTR7HDAC8HDAC6DRD1ALOX5AP | |
| SCHEMBL9430594 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL777619 | 0.71 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL8409334 | 0.71 | CYP2A6 (0.44) | HTR7HDAC8HDAC6DRD1ALDH1A1 | |
| SCHEMBL30006762 | 0.71 | CYP2A6 (0.44) | HTR7HDAC8HDAC6DRD1ALDH1A1 | |
| SCHEMBL2105680 | 0.71 | BACE1 (0.31) | — | |
| SCHEMBL2105682 | 0.70 | — | — | |
| SCHEMBL10602334 | 0.66 | ALDH1A1 (0.33) | ALDH1A1HPGD | |
| SCHEMBL945670 | 0.66 | HTR7 (0.50) | HTR7HDAC8HDAC6DRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382206-B1 | Perfluoroalkyl-containing compound | SAGAMI CHEM RES (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5066795-A | Reagent for perfluoroalkylation, heterocyclic sulfur or selenium compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0382206-A1 | Perfluoroalkyl-containing compound | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1990-08-16 | — | — | EP | disclosed |