Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GABRP | O00591 | 2/20 | 0.48 |
| ▸ | GABRD | O14764 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.48 |
| ▸ | GABRE | P78334 | 2/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20804 | 0.93 | GABRP (0.54) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL713404 | 0.93 | GABRP (0.54) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL5682535 | 0.93 | GABRP (0.54) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1483353 | 0.91 | LMNA (0.50) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Hydrochloric Acid SCHEMBL9804576 | 0.91 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Water SCHEMBL14109989 | 0.91 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Water SCHEMBL14109991 | 0.91 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL9804579 | 0.91 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28840216 | 0.91 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Water SCHEMBL14109993 | 0.91 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621881-A1 | PROCESS FOR INCREASING STABILITY OF POLY(ESTERAMIDES). | MINNESOTA MINING & MFG (US) | 1994-11-02 | — | — | EP | disclosed |
| WO-1993015130-A2 | PROCESS FOR INCREASING STABILITY OF POLY(ESTERAMIDES) | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-08-05 | — | — | WO | disclosed |