⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15976371 | 0.84 | — | — | |
| SCHEMBL6201701 | 0.80 | DNM1 (0.48) | — | |
| SCHEMBL10829120 | 0.78 | — | — | |
| SCHEMBL7526104 | 0.77 | CA12 (0.42) | — | |
| SCHEMBL5932595 | 0.77 | — | — | |
| SCHEMBL24773596 | 0.76 | CHRM1 (0.39) | — | |
| SCHEMBL10827899 | 0.76 | — | — | |
| SCHEMBL14309657 | 0.76 | — | — | |
| SCHEMBL1535816 | 0.74 | CA12 (0.52) | — | |
| SCHEMBL498779 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397012-B1 | Thiolcarbamate granule formulation | HODOGAYA CHEMICAL CO LTD (JP) | 1994-07-20 | — | — | EP | claimed |
| US-5169643-A | Agricultural nematocides impregnated into Fuller's Earth to prolong retention times in soil | HODOGAYA CHEMICAL CO., LTD. (JP) | 1992-12-08 | — | — | US | claimed |
| US-20230242479-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | THE JOHNS HOPKINS UNIVERSTY | 2023-08-03 | — | — | US | disclosed |
| US-11584712-B2 | Alkylamine-substituted perthiocarbamates as dual precursors to hydropersulfide and carbonyl sulfide | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220340570-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2022-10-27 | — | — | US | disclosed |
| US-11352350-B2 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2022-06-07 | — | — | US | disclosed |
| US-20210323952-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2021-10-21 | — | — | US | disclosed |
| US-20210238134-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | NATIONAL SCIENCE FOUNDATION | 2021-08-05 | — | — | US | disclosed |
| EP-0397012-B1 | Thiolcarbamate granule formulation | HODOGAYA CHEMICAL CO LTD (JP) | 1994-07-20 | — | — | EP | disclosed |
| EP-0251827-B1 | NEW CYCLIC ETHER DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-5169643-A | Agricultural nematocides impregnated into Fuller's Earth to prolong retention times in soil | HODOGAYA CHEMICAL CO., LTD. (JP) | 1992-12-08 | — | — | US | disclosed |
| US-4891363-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0251827-A2 | New cyclic ether derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-01-07 | — | — | EP | disclosed |