Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109291 | 0.89 | EGFR (0.40) | RXFP1MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL7199140 | 0.88 | PPARG (0.44) | HDAC6NR1H4TP53KDM4EALDH1A1 | |
| SCHEMBL3900613 | 0.83 | NPC1 (0.44) | RXFP1MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL2164286 | 0.82 | EPHX2 (0.37) | ALDH1A1TDP1 | |
| SCHEMBL12804143 | 0.81 | MAPT (0.33) | RXFP1MAPTTP53KDM4EPPARG | |
| SCHEMBL29365566 | 0.81 | MAOB (0.40) | HDAC6RBP4KMOKDM4EALDH1A1 | |
| SCHEMBL101259 | 0.81 | MAOB (0.40) | HDAC6RBP4KMOKDM4EALDH1A1 | |
| SCHEMBL7689792 | 0.81 | HDAC6 (0.37) | HDAC6RBP4NR1H4MAPTTP53 | |
| SCHEMBL29481344 | 0.78 | NPC1 (0.42) | RXFP1MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL1276012 | 0.78 | NPC1 (0.42) | RXFP1MAPTTP53KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281646-A | Emulsion polymerization of aromatic vinyl compound and vinyl cyanide in the presence of a conjugated diene rubber, flocculation, slurrying, pelletization | SUMITOMO CHEMICAL COMPANY, LIMITED AND SUMITOMO DOW LIMITED (JP) | 1994-01-25 | — | — | US | disclosed |