Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | ATM | Q13315 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276012 | 0.92 | NPC1 (0.42) | NPC1MAPTRAB9AATMKDM4E | |
| SCHEMBL29481344 | 0.92 | NPC1 (0.42) | NPC1MAPTRAB9AATMKDM4E | |
| SCHEMBL9261254 | 0.85 | NPC1 (0.38) | NPC1MAPTRAB9AATMKDM4E | |
| SCHEMBL31419499 | 0.83 | NPC1 (0.43) | NPC1MAPTRAB9AATMKDM4E | |
| SCHEMBL2548304 | 0.83 | KDM4E (0.47) | NPC1MAPTRAB9AKDM4EMEN1 | |
| SCHEMBL9420192 | 0.83 | HDAC6 (0.37) | NPC1MAPTRAB9AATMKDM4E | |
| SCHEMBL7109291 | 0.82 | EGFR (0.40) | NPC1MAPTRAB9AKDM4EKMT2A | |
| Bumetrizole SCHEMBL10836210 | 0.82 | NPC1 (0.52) | NPC1MAPTRAB9AATMKDM4E | |
| Bumetrizole SCHEMBL2398487 | 0.81 | NPC1 (0.53) | NPC1MAPTRAB9AATMKDM4E | |
| Bumetrizole SCHEMBL8603228 | 0.81 | NPC1 (0.53) | NPC1MAPTRAB9AATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088513-A1 | RESIN ADDITIVE COMPOSITION AND RESIN COMPOSITION | ADEKA CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| EP-1505086-B1 | Method of manufacturing polyelectrolyte | SONY CORP (JP) | 2009-02-11 | — | — | EP | disclosed |
| CN-1031341-C | Process for preparing benzotriazole derivatives | CIBA GEIGY AG (CH) | 1996-03-20 | — | — | CN | disclosed |
| US-4999433-A | Process for the preparation of benzotriazole derivatives | CIBA-GEIGY CORPORATION (US) | 1991-03-12 | — | — | US | disclosed |
| US-4326061-A | ULTRAVIOLET RADIATION, STABILIZERS | THE B. F. GOODRICH COMPANY (US) | 1982-04-20 | — | — | US | disclosed |
| US-4233400-A | HIGH CONTRAST IMAGE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1980-11-11 | — | — | US | disclosed |
| US-4169733-A | PRETREATMENT WITH NITROGEN HETEROCYCLE SUBSTITUTED WITH MERCAPTO, THIOKETONE OR THIOETHER GROUP OF SILVER HALIDE EMULSION CONTAINING A TETRAZOLIUM COMPOUND | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1979-10-02 | — | — | US | disclosed |
| US-4073770-A | Substituted decahydroquinolines and their use as ultraviolet light stabilizers | THE B. F. GOODRICH COMPANY (US) | 1978-02-14 | — | — | US | disclosed |