Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541075 | 0.88 | TSHR (0.35) | TSHRALDH1A1TP53LMNAMEN1 | |
| SCHEMBL7728997 | 0.86 | TSHR (0.33) | TSHRALDH1A1TP53LMNAMEN1 | |
| SCHEMBL9420217 | 0.81 | TSHR (0.33) | TSHRALDH1A1TP53LMNAMEN1 | |
| SCHEMBL4162551 | 0.80 | LMNA (0.48) | TSHRALDH1A1LMNAMEN1BLM | |
| SCHEMBL9333204 | 0.79 | ALDH1A1 (0.46) | TSHRALDH1A1TP53 | |
| SCHEMBL9452773 | 0.76 | MAPT (0.34) | TSHRALDH1A1LMNAMEN1BLM | |
| SCHEMBL6523952 | 0.74 | TSHR (0.38) | TSHRALDH1A1TP53 | |
| SCHEMBL19371484 | 0.73 | TET2 (0.32) | LMNAMEN1BLMHBBKMT2A | |
| SCHEMBL9110836 | 0.72 | — | — | |
| SCHEMBL9548584 | 0.70 | LMNA (0.42) | TSHRALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183938-A | N,N'-bis(4,4,4-trinitrobutyryl)hydrazine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1993-02-02 | — | — | US | claimed |
| US-5292951-A | 1,3,4-oxadiazoles containing the pentafluorothio (SF5) group | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1994-03-08 | — | — | US | disclosed |
| US-5274103-A | 1,3,4-Oxadiazoles containing the pentafluorothio (SF5) Group | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1993-12-28 | — | — | US | disclosed |
| US-5241071-A | 2-polynitroalkyl-5-perfluoroalkyl-1,3,4-oxadiazoles | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1993-08-31 | — | — | US | disclosed |
| US-5183938-A | N,N'-bis(4,4,4-trinitrobutyryl)hydrazine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1993-02-02 | — | — | US | disclosed |
| US-4683085-A | Polyazido esters | ROCKWELL INTERNATIONAL CORPORATION (US) | 1987-07-28 | — | — | US | disclosed |
| US-4683085-A | Polyazido esters | ROCKWELL INTERNATIONAL CORPORATION (US) | 1987-07-28 | — | — | US | disclosed |
| US-4683086-A | Azido derivatives of pentaerythritol | ROCKWELL INTERNATIONAL CORPORATION (US) | 1987-07-28 | — | — | US | disclosed |
| US-4141910-A | PLASTICIZERS, OXIDIZERS | ROCKWELL INTERNATIONAL CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |