Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11882014 | 0.83 | LMNA (0.32) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL9124317 | 0.80 | LMNA (0.41) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL9420217 | 0.79 | TSHR (0.33) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL4162551 | 0.78 | LMNA (0.48) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL328634 | 0.78 | LMNA (0.48) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL3998009 | 0.78 | LMNA (0.48) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL15282023 | 0.76 | LMNA (0.34) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL15443091 | 0.74 | LMNA (0.44) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL15570883 | 0.74 | LMNA (0.44) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL44822 | 0.74 | ALDH1A1 (0.47) | LMNAMEN1KMT2ABLMHBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292951-A | 1,3,4-oxadiazoles containing the pentafluorothio (SF5) group | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1994-03-08 | — | — | US | disclosed |
| US-5274103-A | 1,3,4-Oxadiazoles containing the pentafluorothio (SF5) Group | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1993-12-28 | — | — | US | disclosed |
| US-5241071-A | 2-polynitroalkyl-5-perfluoroalkyl-1,3,4-oxadiazoles | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1993-08-31 | — | — | US | disclosed |